Hello,
Same old story. Who comes first.... Thief or Cop?
Don't Take me otherwise, what I mean to say is; there may be cases where Symantec is not detecting the Threat. In that case, Symantec would need your Assistance.
Let us know about it. We would like to hear from you.
If you feel there is a new varient of an old Threat or a new Threat and Symantec is not catching, you would have to submit suspicious files to verify whether those files are Clean or Malicious.
There are 2 ways to catch the suspicious files.
1) Manual - You may find some files which shouldn't be there on the computer. You could submit those files. Yes, sometimes you feel those files are hidden. in that case, go for option 2.
2) Automatted - Run the Symantec Support Tool with Loadpoint Analysis and it would collect the suspicious files for you. Check the Below:
Using Symantec Support Tool, how do we Collect the Suspicious Files and Submit the same to Symantec Security Response Team.
https://www-secure.symantec.com/connect/articles/using-symantec-support-tool-how-do-we-collect-suspicious-files-and-submit-same-symantec-sec
As told above, Prevention is far better than Remediation. (Thanks Sandra...!), So what will you do to Preventing this thing from happening.
You may also find your answers in the Symantec Knowledgebase Article as given above:
Scanning a file with a competitor's antivirus program detects a virus, but scanning with Symantec AntiVirus or Symantec Endpoint Protection does not
http://www.symantec.com/business/support/index?page=content&id=TECH98929
Few Documents which may be helpful in answering all your How, why, what and where questions.
1) About viruses and security risks
http://www.symantec.com/business/support/index?page=content&id=TECH140085
2) What to do when you suspect that a Symantec AntiVirus product is not detecting viruses
http://www.symantec.com/business/support/index?page=content&id=TECH99222
3) Security Best Practice Recommendations
http://www.symantec.com/business/support/index?page=content&id=TECH91705
4) Best practices for troubleshooting viruses on a network
http://www.symantec.com/business/support/index?page=content&id=TECH122466
5) Common loading points for viruses, worms, and Trojan horse programs on Windows 2000/XP/2003
http://www.symantec.com/business/support/index?page=content&id=TECH99331
6) About creating a plan to respond to viruses and security risks
http://www.symantec.com/business/support/index?page=content&id=HOWTO27199
7) How to prevent a virus from spreading using the "AutoRun" feature
http://www.symantec.com/business/support/index?page=content&id=TECH104447
Hope I have tried my Level Best to Answer you.