I have found the issue. Looking at the Symentec help tool it lists the manager as Enterprise but I am running Small Business, see the screen shot of the login page for protectio manager
Looks to be a fault in RU3, can this line be edited in registry?
Endpoint Protection Manager Summary
Version Registry
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12.1.3001.165
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Type Registry
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EntEdition_LT
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Database Configurations
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Database Type
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SQL Anywhere
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Database Host
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localhost
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Database User
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DBA
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Database Test
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SELECT count(*) FROM CONNECTION_TEST
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