HI,
Check this artical
https://www-secure.symantec.com/connect/articles/issue-related-low-disk-space
It is recommended to utilize the following articles for additional information:
1) Disk Space Management procedures for the Symantec Endpoint Protection Manager
http://www.symantec.com/docs/TECH96214
2) Symantec Endpoint Protection virus definition folder consumes a large amount of disk space
http://www.symantec.com/docs/TECH102927
3) For information on monitoring Server Health from Symantec Endpoint Protection Manager and Receive Notification, view the article linked below:
Monitoring Server Health on Symantec Endpoint Protection Manager
http://www.symantec.com/docs/TECH122731
Some Best Practice Articles:
1) Best Practices for configuring the number of content revisions to keep in Symantec Endpoint Protection Manager
http://www.symantec.com/docs/TECH92225
2) Troubleshooting Content Delivery to the Symantec Endpoint Protection client
http://www.symantec.com/docs/TECH106034