Hi,
Vote up for Mithun, Earlier I also need guidance about multiple remote site location SEPM architecture.thanks to Mithun and Sumit , they suggeted me to deploy GUP and shared few links which is above Mithun posted. You can have single SEPM at your central site with a failover server or replication server, and at your remote sites, please assigan any good hardware system which would be your normal SEP client, prefarably any application server. It will receive update from SEPM and will distribute to your remote site clients, Clinets will only talk to SEPM server to receive any policy according to heartbeat which you defined. GUP can be configured for your remote site on your central SEPM server, for bandwidth issue bandwidth can be throtted on SEPM for remote sites. GUP is the best option for your remote sites to update thousands of systems without bandwitdht issue.
Please go through following links for GUP details and architecture for SEPM for remote sites.
http://www.symantec.com/docs/HOWTO55088
http://www.symantec.com/docs/HOWTO26781
http://www.symantec.com/docs/HOWTO55065
http://www.symantec.com/docs/HOWTO55066
http://www.symantec.com/docs/HOWTO55064
http://www.symantec.com/docs/HOWTO55086
Regards,
Ajay Singh