Is this an unmanaged client? It sounds like it is.
12/30/2012 8:37:56 AM Blocked 3 Outgoing UDP 239.255.255.250 01-00-5E-7F-FF-FA 1900 192.168.0.143 00-10-18-EA-74-75 1900 C:\Windows\System32\svchost.exe LOCAL SERVICE NT AUTHORITY Default 18 12/30/2012 8:36:54 AM 12/30/2012 8:37:00 AM Block UPnP Discovery
It's legitimate traffic that is being blocked by the Block UPnP Discovery rule
Universal Plug and Play (UPnP) is a set of networking protocols that permits networked devices, such as personal computers, printers, Internet gateways, Wi-Fi access points and mobile devices to seamlessly discover each other's presence on the network and establish functionalnetwork services for data sharing, communications, and entertainment. UPnP is intended primarily for residential networks without enterprise class devices.
You can allow it by opening the SEP GUI and under Network Threat Protection click Options >> Configure Firewall Rules
Select the Block UPnP Discovery and hit Edit
Under Action, select Allow this traffic and click OK
You should not see the message for this rule any more.
You can disable the notifications completely by going to NTP >> Options >> Configure Settings and on the Notification tab, select the option to not show messages. However, this will disable the message for all rules and is not really recommended. But if you do, you would need to keep a closer eye on your logs.