In your case client can able to communicatewith SEPM. But SEPM is not processing the client data.
Problem
When checking the computer status in Symantec Endpoint Protection Manager (SEPM), clients say that they are not reporting status.
Symptoms
Can't confirm if commands were sent successfully.
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Status page shows various failures.
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No entries in the Virus Definitions Distribution box.
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No data about the clients at all in SEPM.
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Clients and SEPM don't show the same data for definition dates
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"The data folder disk space is full" errors in the exsecars.log file
Reference:
Clients cannot send data back to Symantec Endpoint Protection Manager
http://www.symantec.com/docs/TECH105348
Kindly try this troubleshooting step:
1. Browse to \Program Files\Symantec\Symantec Endpoint Protection Manager\data\outbox\agentinfo
2. Look for any .err files or tmp files & Dat files
3. If you find anything which is not processed by sepm then it might be the reason for the client data loss
4. Stop SEPM services from services.msc
5. Delete all the files inside the location \Program Files\Symantec\Symantec Endpoint Protection Manager\data\inbox\agentinfo
6. Restart the SEPM services.
Check the SEPM now if still issue persist go for step 7
7. Run the Management server configuration wizard.
Note: While running Management server configuration wizard it requires Database password. if you running SEP 12.1.2 it wont prompt you for DB password.
Kindly update us the status .... thanks