We have a test environment setup with SEP v12.1 RU1 installed on it. We have attached to this about ten clients all running the v12.1 client. These have a mix of Lotus Notes clients installed but most are v8.5.2 and v8.5.3
We used the SEPM Manager to update four of these machines (3 Windows 7 and 1 XP) to the v12.1 RU1 client.
On all clients Lotus Notes failed to work after the system was rebooted and the following error was generated in Lotus Notes..
[0CC4:0002-0CD0] Thread=[0CC4:0002-0CD0]
Stack base=0x00137A84, Stack size = 6968 bytes
PANIC: semaphore invalid or not allocated
The only way to fix the issue is to remove SEP/Lotus Notes & Java and clear out all remaining disk entries and registry entries (you must do this or Lotus Notes will not even install).
We don't use email scanning on clients btw as this is done using SMSDOM on the Noted mail servers.
Re-Install Lotus Notes then SEP manually and finally Java the issue is then resolved.
I've rased it with support but wondered if anyone else has come across this yet with v12.1 RU1 and Lotus Notes clients???