Currently, Symantec says they support these distro's:
Red Hat® Enterprise Linux 3.0 ES (RHEL3ES)
SuSE™ LINUX Enterprise Server 9 (SLES9)
Novell® Linux Desktop 9 (NLD9)
We have are not using these distro's however. Has anyone else been able to get it running on a different distro than listed above? Is it recommended for only the three above or is it a use at your own risk should you choose to put it on something different.