Follow the steps below to change the location of the sem5.db database file for Symantec Endpoint Protection Manager (SEPM):
Go to services.msc
Stop the Symantec Endpoint Protection Manager Service
Stop the Symantec Embedded Database Service
Go to \Program Files\Symantec\Symantec Endpoint Protection Manager\db and copy all the files and paste it to the new drive
Click Start
Click run
Type regedit
Go to HKey_Local_Machine\system\CurrentControlSet\Services\ASANYs\Parameters\ click on the Parameters option in the right hand side column and change the path of the sem5.db database file to the new location as New Drive:\Folder name
Restart the Symantec Embedded Database Service from services.msc
Go to Administrative Tools
Click on Data Sources (ODBC)
Click on System DSN tab
Click on Configure button
Highlight the database tab and replace the path for the sem5.db file and ensure connectivity by clicking on Test Connection
Go to Management Server configuration Wizard and perform the server reconfiguration